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Is 2-DG a Revolutionary Invention?

Is 2-DG a Revolutionary Invention?

As country is facing COVID-19 pandemic a much needed anti-covid drug named 2-DEOXY-D-GLUCOSE is launched by DRDO (Defence Research and Development Organisation) and approved by DCGI (Drugs Controller General of India). This drug is developed in conjunction by the Institute of Nuclear Medicine and Allied Sciences (lab of DRDO) in collaboration with Dr Reddy’s Laboratories, Hyderabad.

According to reports in April 2020, team has started experiment and found this molecule is effective against COVID-19.  In May-2020 they conducted clinical phase 2 trials and after its success in between December 2020 & March 2021 conducted phase 3 trials.

How Does It Work?

As per literary data 2-DG possess direct action on covid-19 infection rather than any indirect pathways to act. It accumulates virus infected cells of body and prevents their multiplication and further growth. It also stop the energy product of virus as a result viral synthesis come to an end. Because of this property 2-DG medicine is unique and very effective against COVID-19.

It also reduce the oxygen dependency.

Strong Point:

As per government reports 2-DG is a generic molecule and an analogue of glucose that’s why it can be easily produced and made available in large quantities.

Salient Features:

Name: 2-DG (2-Deoxy-D-Glucose)

Form: Powder, Sachet

Mass: 5.85g

Route of Administration: Oral

Protect From Moisture

Effective: Moderate to severe covid infected patients.

Safe and improve recovery among covid patients.

 

References:

·          sciencereporter.niscair.res.in/home/article/424

·         https://www.expresspharma.in/drdo-launches-anti-covid-drug-2-dg/

·         https://blog.forumias.com/dcgi-approves-2-deoxy-d-glucose-2-dg-an-anti-covid-drug-developed-by-drdo/

·         https://blog.trishuldefenceacademy.com/defence-news/drdo-2-dg-medicine-for-covid-19-launched-in-india/